Category 6 - PATHOLOGY SERVICES
PN.7.22
DPYD genotyping to diagnose or predict fluoropyrimidine-induced toxicity
The list of gene variants analysed should be selected in line with current clinical guidelines, such as the eviQ guidelines, and should include direct detection of at least the following variants:
• NM_000110.4(DPYD):c.1905+1G>A
• NM_000110.4(DPYD):c.1679T>G
• NM_000110.4(DPYD):c.2846A>T
• NM_000110.4(DPYD):c.1129-5923C>G
Legend
- Assist - Addition/Deletion of (Assist.)
- Amend - Amended Description
- Anaes - Anaesthetic Values Amended
- Emsn - EMSN Change
- Fee - Fee Amended
- Renum - Item Number Change (renumbered)
- New - New Item
- NewMin - New Item (previous Ministerial Determination)
- Qfe - QFE Change